Principal investigators

Masayuki Hirata

Brain-machine interfaces

Main Lab Location:

Osaka Univ. (Suita Campus)

Other Affiliations:

Specially Appointed Professor
Department of Neurological Diagnosis and Restoration
Osaka University Graduate School of Medicine

Global Center for Medical Engineering and Informatics
Osaka University
Department of Neurosurgery
Osaka University Graduate School of Medicine

Mailing Address:

2-2 Yamadaoka, Suita, Osaka 565-0871 Japan


mhirata at


My research focuses on the brain machine interfaces (BMIs). With this technique, the “thought” of a man can be translated into action. The brain signals obtained with intracranial electrodes are decoded in real-time in order to control robots or computers only by thinking, without using his/her own motor system. Our goal is the clinical application of BMI which support the communication and movements of people with severe motor disabilities such as with tetraplegia or locked-in syndrome.

Selected Publications:

Araki T, Yoshida F, Uemura T, Noda Y, Yoshimoto S, Kaiju T, Suzuki T, Hamanaka H, Baba K, Hayakawa H, Yabumoto T, Mochizuki H, Kobayashi S, Tanaka M, Hirata M, Sekitani T, et al (in press) Long-term implantable, flexible, and transparent neural interface based on Ag/Au core-shell nanowires. Adv Healthc Mater

Belkacem A, Nishio S, Suzuki T, Ishiguro H, Hirata M, et al (2018) Neuromagnetic decoding of simultaneous bilateral hand movements for multidimensional brain-machine interfaces. IEEE Trans Neural Syst Rehabl Eng 26(6):1301-1310

Matsushita K, Hirata M, Suzuki T, Ando H, Yoshida T, Ota Y, Sato F, Morris S, Sugata H, Goto T, Yanagisawa T, Yoshimine T, et al (2018) A fully implantable wireless ECoG 128-channel recording device for human brain–machine interfaces: W-HERBS. Front Neurosci 12(511):1-11

Hashimoto H, Hasegawa Y, Araki T, et al (2017) Non-invasive detection of language-related prefrontal high gamma band activity with beamforming MEG. Sci Rep 7:14262

Yoshida F, Hirata M, Onodera A, et al (2017) Noninvasive spatiotemporal imaging of neural transmission in the subcortical visual pathway. Sci Rep 7(1):4424

Araki T, Hirata M, Yanagisawa T, et al (2016) Language-related cerebral oscillatory changes are influenced equally by genetic and environmental factors. Neuroimage 142:241–247

Sugata H, Hirata M, Yanagisawa T, et al (2016) Common neural correlates of real and imagined movements contributing to the performance of brain–machine interfaces. Sci Rep 6: 24663

Shayne M, Hirata M, Sugata H, et al (2015) Patient specific cortical electrodes for sulcal and gyral implantation. IEEE Trans Biomed Eng 62(4):1034-41

Yanagisawa T, Hirata M, Saitoh Y, et al (2012) Electrocorticographic control of a prosthetic arm in paralyzed patients. Ann Neurol 71:353-361.

Hirata M, Matsushita K, Suzuki T, et al (2011) A fully-implantable wireless system for human brain-machine interfaces using brain surface electrodes: W-HERBS. IEICE Trans Commun E94-B:2448-2453.

Short Biography:

<Academic appointments>
・Sept. 2003-Sept.2009
Assistant professor, Division of Functional Diagnostic Science, Osaka University Graduate School of   Medicine
・Oct, 2009-Mar, 2016
Associate professor, Department of Neurosurgery, Osaka University Medical School
・April, 2016 -
Endowed Division Professor, Endowed Division of Clinical Neuroengineering, Global Center for Medical Engineering and Information, Osaka University
・April, 2019 -
Specially Appointed Professor, Department of Neurological Diagnosis and Restoration, Osaka University Graduate School of Medicine

<Academic contribution>
・Vice-president, President-elect
International Society for the Advancement of Clinical Magnetoencephalography (ISACM)
・Member of the Executive Committee
Japanese Society for Medical and Biological Engineering
・Vice President
Japan Biomagnetism and Bioelectromagnetics Society
・Councilor of Neurosurgical BMI Forum

2000 Certification of a Neurosurgeon from The Japan Neurosurgical Society
2004 Certification of a Neuroendovascular Surgeon from The Japanese Society for Neuroendovascular Treatment
2006 Certification of a Clinical Neurophysiologist from Japanese Society of Clinical Neurophysiology
2015 Certification of a Clinical Epileptologist from Japan Epilepsy Society

2012     Mimics Innovation Awards 2012
2013     Osaka University 2nd Presidential Awards for Achievement
2014     Osaka University 3rd Presidential Awards for Achievement

Announcements / News:
Lab Members:

Toshiki Yoshimine
・Noriaki Hattori
・Seiji Kameda
Hiroki Hamanaka
・Palmer Jason Allan
・Masahito Inoue
・Hitoshi Maezawa
・Abdi Reza
・Xin He
・Namheon Kim
・Masahito Mihara
・Fumiaki Yoshida
・Takashi Moriwaki
・Hiroaki Hashimoto
・Yosuke Fujimoto
・Yuka Omura
・Kanae Kusakabe
・Takuma Asano

・Izumi Kawaguchi
・Yoshiko Takeuchi
・Kumiko Fukunaga
・Harumi Takamura
・Keiko Kawamura