Ken-ichi Okada: “Elucidation of the mechanism of schizophrenia using eye movement”

October 4, 2019  Friday Lunch Seminar
12:15 〜 13:00

CiNet 1F Conference Room

“Elucidation of the mechanism of schizophrenia using eye movement”

Ken-ichi Okada

Graduate School of Frontier Biosciences
Osaka University

Host PI: Ichiro Fujita


Schizophrenia is a chronic mental disorder that affects various cognitive functions. Patients with schizophrenia (SZs) suffer from positive symptoms (e.g., delusion, hallucinations), negative symptoms (e.g., reduced motivation), cognitive impairments (e.g., deficits in attention and memory), and also showed eye movement abnormality. The eye movement abnormality could be reflected underlying computational and information processing deficits in SZs. We analyzed eye movement of SZs under free-viewing conditions and found that SZs have an anomaly in inhibition of return (IOR), the mechanism that inhibits orienting to previously fixated or attended locations. The impaired IOR was a cause of the limited scanning and could influence daily visual search behavior of SZs. This result is consistent with the view that the deficit in predictive coding underlies heterogeneous symptoms of SZs.

About CiNet’s Friday Lunch Seminars:
The Friday Lunch Seminar is CiNet’s main regular meeting series, held every week at 12:15 in the beautiful main lecture theatre on the ground floor at CiNet. The talks are typically 40mins long and orientated towards an inter-disciplinary audience. They are informal, social, and most people bring their own lunch to eat during the talk. They are open to anyone who is feeling curious and wants to come, regardless of where you work.