Anna-Lisa Schuler “Prenatal origins of language, dopaminergic origins of creativity and their implications on brain stimulation targets”

November 21, 2018
CiNet 1F Conference Room
(We may stop the seminar at 13:00, and continue the discussion until 13:15.)

Anna-Lisa Schuler
Research Fellow
Department of Pediatrics and Adolescent Medicine
Medical University of Vienna

Host : Hiromasa TakemuraKida Group

Imaging the fetal brain has emerged in the last two decades and provides the breeding ground for predictive models of lifetime development in health and disease. In a follow-up study the linguistic functions of children were assessed in terms of fMRI and behavioral assessment. The emerging asymmetry of the superior temporal sulcus served as prominent marker for fetal brain development. Both approaches, imaging as well as cognitive assessment can be associated with the fetal asymmetry of the superior temporal sulcus. There is a hint towards combined cortical-subcortical effects.

Moreover, in young adults cortical-subcortical connections, as revealed by fMRI combined with questionnaire data, were shown to be involved in different personality traits of creativity.

Lifespan observations on the development of cognitive functional networks provide new insights into possible cortical stimulation targets for neurostimulation applications.

In this talk I will (1) give an overview on the predictive value of fetal brain structure, focusing on potential dopaminergic pathways involved in their outcomes. Furthermore, I will (2) talk about cortical-subcortical networks associated with creative personality aspects. Finally, I will (3) give an outlook on how these observations can inform neurostimulation experiments in terms of effective targeting strategies, and thereby improve their clinical and scientific applications.