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栗原 実紗: “How does melatonin contribute to emotion regulation?”

 

2019年6月24日(月)
13:30 ~
会場 : CiNet 1F 大会議室

“How does melatonin contribute to emotion regulation?”

国立研究開発法人 理化学研究所
脳神経科学研究センター リサーチアシスタント
栗原 実紗

担当 : 春野 雅彦(PI)

Abstract:
Emotion dysregulation is often associated with antisocial behaivours, and regulating emotions is important for optimal decision making and for social functioning. However, it has been unclear why humans cannot regulate emotions in social interactions. Sleep has been considered to play a key role in emotion regulation, but little is known about the relationship between melatonin, a sleep hormone, and emotion regulation.
To understand the neuroendocrine process of emotion regulation, we administered melatonin or placebo to healthy participants, and we investigated how decision-making would change after melatonin administration. As we predicted, melatonin increased the selection of rejection in Ultimatum Game compared with placebo controls, but we could not find a significant increase in sleepiness and emotional reactivity from the self-reports after melatonin administration. Combined with our second study, it is expected to see the process why humans failed to do rational decision making after melatonin administration.