Konrad Wagstyl: “BigBrain: Deep learning of cerebral cortex microstructure”

2018年12月19日(水)
12:15~13:15
(セミナー終了後13:15まで講師とディスカッションが可能です。)
会場 : CiNet 1F 大会議室

“BigBrain: Deep learning of cerebral cortex microstructure”

Konrad Wagstyl
Postdoctoral Research Associate
Department of Psychiatry
University of Cambridge

担当 : 竹村 浩昌黄田グループ

Abstract:
The cerebral cortex has a layered microstructure that varies depending on cortical area, local geometry and is altered by neurological and psychiatric pathologies. In this talk I will discuss the application of deep learning to analysing ex vivo and in vivo cortical microstructure. First I will explore how deep learning can be used to segment the layers and areas of the cerebral cortex of the BigBrain, a high resolution 3D histological dataset. I will then show how these can be used to interpret in vivo patterns of cortical structure measured using MRI. Finally, I will show how we are using deep learning to detect and segment microstructural lesions in hospital MRI scans of patients with epilepsy, caused by focal cortical dysplasias. This project has involved an open science approach and now has 23 epilepsy centres worldwide collaborating to create a cohort of patients.

https://academic.oup.com/cercor/article/28/7/2551/4975486