{"id":1440,"date":"2019-11-13T18:47:00","date_gmt":"2019-11-13T09:47:00","guid":{"rendered":"http:\/\/cinetjp-static3.nict.go.jp\/english\/?p=1440"},"modified":"2022-10-12T10:52:30","modified_gmt":"2022-10-12T01:52:30","slug":"20191204_4202","status":"publish","type":"event","link":"http:\/\/cinetjp-static3.nict.go.jp\/english\/event\/20191204_4202\/","title":{"rendered":"NICT-IFReC Joint Seminar: Yuka Sasaki \u201cOpponent neurochemical and functional processing in NREM and REM sleep in visual perceptual learning\u201d"},"content":{"rendered":"\n<p>NICT-IFReC Joint Seminar<\/p>\n\n\n\n<p>December&nbsp;13, 2019<br>16:00-17:00<br>CiNet 1F Conference Room<\/p>\n\n\n\n<p>Yuka Sasaki<br>Professor<br>Brown University<\/p>\n\n\n\n<p>Hosts:<br>Center for Information and Neural Networks (CiNet), National Institute of Infromraiton and Neural Networks (NICT)<br>Osaka University Immunology Frontier Research Center (IFReC)<\/p>\n\n\n\n<p>Abstract:<br>Sleep is beneficial for learning. However, whether NREM or REM sleep facilitates learning, whether the learning facilitation results from plasticity increases or stabilization and whether the facilitation results from learning-specific processing are all controversial. Here, after training on a visual task we measured the excitatory and inhibitory neurochemical (E\/I) balance, an index of plasticity measured by magnetic resonance spectroscopy in human visual areas, for the first time, while subjects slept. Off-line performance gains of presleep learning were associated with the E\/I balance increase during NREM sleep, which also occurred without presleep training. In contrast, increased stabilization was associated with decreased E\/I balance during REM sleep only after presleep training. These indicate that the above-mentioned issues are not matters of controversy but reflect opposite neurochemical processing for different roles in learning during different sleep stages: NREM sleep increases plasticity leading to performance gains independently of learning, while REM sleep decreases plasticity to stabilize learning in a learning-specific manner.<\/p>\n","protected":false},"featured_media":0,"template":"","acf":[],"_links":{"self":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/english\/wp-json\/wp\/v2\/event\/1440"}],"collection":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/english\/wp-json\/wp\/v2\/event"}],"about":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/english\/wp-json\/wp\/v2\/types\/event"}],"wp:attachment":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/english\/wp-json\/wp\/v2\/media?parent=1440"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}