Tomoo Mano

Main Lab Location:

Osaka Univ. (Suita Campus)

Specific Research Topic:

Neural plasticity,Neurorehabilitation



Mailing Address:

3B3-2(BMI Office 10)
1-4 Yamadaoka, Suita City, Osaka
565-0871 Japan


mano at

My research focuses on clinical development for Neurorehabilitation. I utilize non-invasive brain stimulation techniques, including rTMS and tDCS, which can be used to help recover motor function and cognitive function in neuromuscular disease and dementia.

The goal of my research is to understand the mechanisms underlying plastic changes in the human central nervous system (CNS) and to develop novel therapeutic approaches for functional recovery based on these advances.

Selected Publications:

Mano T. Camptocormia Induced by a Dopaminergic Agonist. Clin Neuropharmacol.2018

Yokoe M, Mano T, Maruo T, Hosomi K, Shimokawa T, Kishima H, Oshino S, Morris S, Kageyama Y, Goto Y, Shimizu T, Mochizuki H, Yoshimine T, Saitoh Y. The optimal stimulation site for high-frequency repetitive transcranial magnetic stimulation in Parkinson's disease: A double-blind crossover pilot study. J Clin Neurosci. 2018

Banno H, Katsuno M, Suzuki K, Tanaka S, Suga N, Hashizume A, Mano T, Araki A, Watanabe H, Fujimoto Y, Yamamoto M, Sobue G. Swallowing markers in spinal and bulbar muscular atrophy. Ann Clin Transl Neurol. 2017

Yamada K, Yuan J, Mano T, Takashima H, Shibata M. Arthropathy-related pain in a patient with congenital impairment of pain sensation due to hereditary sensory and autonomic neuropathy type II with a rare mutation in the WNK1/HSN2 gene. BMC Neurol. 2016

Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Hijikata Y, Tanaka S, Takatsu J, Watanabe H, Yamamoto M, Sobue G. Head Lift Exercise Improves Swallowing Dysfunction in Spinal and Bulbar Muscular Atrophy. Eur Neurol. 2015

Mano T, Nishi R, Kobayashi Y, Matsuo K, Kobayashi Y, Kakehi A. The novel quantitative measures of gait and posture in Parkinson's disease:cross-sectional analysis. Clinical Neurol. 2015

Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Araki A, Watanabe H, Tanaka S, Yamamoto M, Sobue G. Tongue pressure as a novel biomarker of spinal and bulbar muscular atrophy. Neurology. 2014

Mano T, Katsuno M, Banno H, Suzuki K, Suga N, Hashizume A, Tanaka F, Sobue G. Cross-sectional and longitudinal analysis of an oxidative stress biomarker for spinal and bulbar muscular atrophy. Muscle Nerve. 2012