{"id":2301,"date":"2017-02-13T15:01:00","date_gmt":"2017-02-13T06:01:00","guid":{"rendered":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/?post_type=event&p=2301"},"modified":"2022-10-09T15:03:15","modified_gmt":"2022-10-09T06:03:15","slug":"20170213_2532","status":"publish","type":"event","link":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/event\/20170213_2532\/","title":{"rendered":"5th CiNet Monthly Seminar : \u5c71\u4e0b \u8cb4\u4e4b \u201cProjection-specific regulation of large-scale sensorimotor signaling in the neocortex\u201d"},"content":{"rendered":"\n

CiNet Monthly Seminar<\/strong><\/p>\n\n\n\n

2017\u5e743\u67086\u65e5\uff08\u6708\uff09
16:00 ~ 17:00
\u4f1a\u5834 \uff1a CiNet\u30001F\u3000\u5927\u4f1a\u8b70\u5ba4<\/p>\n\n\n\n

\u201cProjection-specific regulation of large-scale sensorimotor signaling in the neocortex\u201d<\/p>\n\n\n\n

\u540d\u53e4\u5c4b\u5927\u5b66\u3000\u74b0\u5883\u533b\u5b66\u7814\u7a76\u6240
\u5c71\u4e0b \u8cb4\u4e4b
http:\/\/www.yamashitalab.org\/<\/p>\n\n\n\n

\u62c5\u5f53 :\u00a0\u7fbd\u5009\u4fe1\u5b8f<\/a>\u3000(\u6c60\u8c37\u30b0\u30eb\u30fc\u30d7<\/a>)<\/p>\n\n\n\n

Abstract:
How sensory information is processed in parallel by distributed neural circuits in the neocortex remains largely unknown. By making in vivo whole-cell recordings in primary somatosensory barrel cortex (S1) of awake behaving mice, I have investigated how S1 neurons projecting to primary motor cortex (M1-p neurons) and those projecting to secondary somatosensory cortex (S2-p neurons) compute incoming sensory information and generate functionally-tuned signal outputs. My recordings revealed that M1-p and S2-p neurons had distinct intrinsic membrane properties and exhibited markedly different membrane potential dynamics during behavior. Most strikingly, M1-p neurons rapidly and transiently signal onset of tactile input, whereas S2-p neurons summate synaptic input, signaling repetitive touch (Ref. 1). Recently I have examined learning-induced changes in membrane potential dynamics of M1-p and S2-p neurons using thirsty mice that learned to lick for water reward after whisker stimulation (Ref. 2). Through training of the task, long-lasting biphasic depolarization became correlated with task performance in S2-p, but not M1-p neurons. Furthermore, after task learning, a lick-related depolarization was emerged in S2-p, not M1-p, neurons. My data highlight the cellular basis of pathway-specific generation of large-scale sensorimotor signals in the neocortex during behavior.<\/p>\n\n\n\n

References:
1. Yamashita et al. (2013) Neuron 80, 1477-1490.
2. Yamashita & Petersen (2016) eLife 5, e15798.<\/p>\n\n\n\n

About CiNet\u2019s Monthly Seminar:<\/strong>
In CiNet Monthly Seminar, distinguished external (national and international) speakers will give a lecture about their latest work. The lecture will be held once a month from 16:00 at the CiNet main lecture theatre, followed by an informal discussion in the coffee room. List of speakers will be announced in advance. Everyone is welcome to attend, and welcome to join the after seminar discussion.<\/p>\n\n\n\n

\u4eca\u5f8c\u306e\u4e88\u5b9a\uff1a<\/p>\n\n\n\n

# 6\u00a0\u00a0 \u00a04\u670814\u65e5\uff08\u91d1\uff09:\u00a0Functional engineering of astrocytes and mind<\/a>
\u677e\u4e95 \u5e83\u3000\u6771\u5317\u5927\u5b66\u3000\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1<\/p>\n\n\n\n

# 7\u00a0\u00a0\u00a0 5\u670815\u65e5\uff08\u6708\uff09:\u00a0Sensory gating during voluntary movement: neural correlates in the cortical and subcortical network<\/a>
\u95a2 \u548c\u5f66\u3000\u56fd\u7acb\u7cbe\u795e\u30fb\u795e\u7d4c\u533b\u7642\u7814\u7a76\u30bb\u30f3\u30bf\u30fc<\/p>\n\n\n\n

# 8    6\u67085\u65e5\uff08\u6708\uff09: TBA
Fang FANG, School of Psychological and Cognitive Sciences, Peking University<\/p>\n\n\n\n

# 9    7\u670828\u65e5\uff08\u91d1\uff09: Building Lifelike Physical Characters
\u5c71\u6839 \u514b\u3000Disney Research<\/p>\n\n\n\n

#10    8\u67084\u65e5\uff08\u91d1\uff09: TBA
\u677e\u5d0e \u653f\u7d00\u3000\u6771\u4eac\u5927\u5b66\u3000\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1<\/p>\n\n\n\n

#11    9\u670822\u65e5\uff08\u91d1\uff09: Prefrontal Cortex and Conscious Perception
Hakwan LAU, Department of Psychology (Cognitive & Behavioral Neuroscience) & Brain Research Institute, UCLA<\/p>\n\n\n\n

#12  10\u670813\u65e5\uff08\u91d1\uff09: TBA
Ralph ADOLPHS, California Institute of Technology<\/p>\n","protected":false},"featured_media":0,"template":"","acf":[],"_links":{"self":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/wp-json\/wp\/v2\/event\/2301"}],"collection":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/wp-json\/wp\/v2\/event"}],"about":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/wp-json\/wp\/v2\/types\/event"}],"wp:attachment":[{"href":"http:\/\/cinetjp-static3.nict.go.jp\/japanese\/wp-json\/wp\/v2\/media?parent=2301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}