イベント

高堂裕平: “Metabolic imaging / measurement for translational research : from mice to human”

 

2016年11月30日  17:00 〜 18:30

CiNet 1F 大会議室
高堂裕平

国立研究開発法人量子科学技術研究開発機構
放射線医学総合研究所
脳機能イメージング研究部

担当 : 吉岡芳親 (PI)

Abstract:

In this seminar, I will talk about several topics related to brain metabolism as well as metabolic imaging/measurement methods. First, I will talk in brief about human magnetic resonance spectroscopy studies for identifying biomarkers of neurodegenerative disorders.
Next, I will present some practical aspects of hyperpolarized 13C experiments in vivo in rodent models using dissolution dynamic nuclear polarization (DNP). Dissolution DNP is a relatively new technique which was launched in 2003. Although there are some common aspects between dissolution DNP and positron emission tomography imaging (an established metabolic imaging modality), a few different aspects need to be considered in both methods. Finally, I will briefly introduce a new in vitro metabolic imaging technique and my current projects related to brain metabolism at the National Institutes for Quantum and Radiological Science and Technology, Chiba.